Enalapril (ACE inhibitor) is indicated for which conditions?

Enalapril (ACE inhibitor) is indicated for which conditions?

• A. Hypertension and congestive heart failure
• B. Hyperglycemia
• C. Hypertrophic cardiomyopathy
• D. Asthma control

Answer: (A)

Enalapril is an ACE inhibitor, and these drugs are commonly used to treat high blood pressure and to improve outcomes in heart failure. They work by blocking the conversion of angiotensin I to angiotensin II, which leads to vasodilation and less aldosterone. The result is lower blood pressure and reduced sodium and water retention. In heart failure, this afterload reduction and favorable remodeling improve symptoms and can reduce mortality. These same mechanisms don’t address high blood sugar, so enalapril isn’t used to treat hyperglycemia. For hypertrophic cardiomyopathy, the focus is on managing obstruction and symptoms with other therapies, not primarily with ACE inhibition. And for asthma control, medications target airway inflammation and bronchoconstriction, not blood pressure or heart failure physiology; plus ACE inhibitors can even cause a cough, which would worsen respiratory symptoms. So the best indication for enalapril among the options is hypertension and congestive heart failure.

Enalapril is an ACE inhibitor, and these drugs are commonly used to treat high blood pressure and to improve outcomes in heart failure. They work by blocking the conversion of angiotensin I to angiotensin II, which leads to vasodilation and less aldosterone. The result is lower blood pressure and reduced sodium and water retention. In heart failure, this afterload reduction and favorable remodeling improve symptoms and can reduce mortality.

These same mechanisms don’t address high blood sugar, so enalapril isn’t used to treat hyperglycemia. For hypertrophic cardiomyopathy, the focus is on managing obstruction and symptoms with other therapies, not primarily with ACE inhibition. And for asthma control, medications target airway inflammation and bronchoconstriction, not blood pressure or heart failure physiology; plus ACE inhibitors can even cause a cough, which would worsen respiratory symptoms.

So the best indication for enalapril among the options is hypertension and congestive heart failure.