Which statement about applying transdermal patches is true?

Which statement about applying transdermal patches is true?

• A. Apply to clean, dry, hairless skin that is not irritated, scarred, burned, broken, or calloused
• B. Apply to wet skin
• C. Apply over a tattoo
• D. Apply on mucous membranes

Answer: (A)

Transdermal patches deliver medication through the skin, so the site chosen must support a reliable seal and stable absorption. The best practice is to place the patch on clean, dry, intact skin that is hairless and free from irritation, scars, burns, broken skin, or calluses. Clean, dry skin allows the adhesive to stick well and ensures the drug is delivered at a predictable rate. Wet, oily, damaged, or irritated skin can reduce adhesion and alter absorption, which can lead to under- or overdosing or local skin reactions. Placing a patch over a tattoo isn’t ideal because the skin in that area can have altered barrier properties and adhesion. Mucous membranes are avoided because they absorb drugs very quickly, increasing the risk of unintended systemic effects. So, applying to clean, dry, hairless skin free of damage best supports safe and effective transdermal patch use.

Transdermal patches deliver medication through the skin, so the site chosen must support a reliable seal and stable absorption. The best practice is to place the patch on clean, dry, intact skin that is hairless and free from irritation, scars, burns, broken skin, or calluses. Clean, dry skin allows the adhesive to stick well and ensures the drug is delivered at a predictable rate. Wet, oily, damaged, or irritated skin can reduce adhesion and alter absorption, which can lead to under- or overdosing or local skin reactions. Placing a patch over a tattoo isn’t ideal because the skin in that area can have altered barrier properties and adhesion. Mucous membranes are avoided because they absorb drugs very quickly, increasing the risk of unintended systemic effects. So, applying to clean, dry, hairless skin free of damage best supports safe and effective transdermal patch use.